MetaCyc Pathway: CMP-legionaminate biosynthesis I in Rhodosporidium toruloides IFO0880

Add experiment(s):


Glutamine--fructose-6-phosphate transaminase (isomerizing):
β-D-fructofuranose 6-phosphate + L-glutamine→D-glucosamine 6-phosphate + L-glutamate
(EC 2.6.1.16)
mRNA_3730 (12098)
mRNA_3731 (12099)
Phosphoglucosamine mutase:
D-glucosamine 6-phosphate→α-D-glucosamine 1-phosphate
(EC 5.4.2.10)
No genes
α-D-glucosamine 1-phosphate + GTP + H+→GDP-D-glucosamine + diphosphate
No genes
GDP-D-glucosamine + acetyl-CoA→GDP-N-acetyl-D-glucosamine + coenzyme A + H+
No genes
GDP-N-acetyl-D-glucosamine→GDP-2-acetamido-2,6-dideoxy-α-D-xylo-hexos-4-ulose + H2O
No genes
GDP-2-acetamido-2,6-dideoxy-α-D-xylo-hexos-4-ulose + L-glutamate→GDP-4-amino-4,6-dideoxy-α-D-N-acetylglucosamine + 2-oxoglutarate
No genes
GDP-4-amino-4,6-dideoxy-α-D-N-acetylglucosamine + acetyl-CoA→GDP-2,4-diacetamido-2,4,6-trideoxy-α-D-glucopyranose + coenzyme A + H+
No genes
GDP-2,4-diacetamido-2,4,6-trideoxy-α-D-glucopyranose + H2O→2,4-diacetamido-2,4,6-trideoxy-α-D-mannopyranose + GDP + H+
No genes
2,4-diacetamido-2,4,6-trideoxy-α-D-mannopyranose + phosphoenolpyruvate + H2O→5,7-diacetamido-3,5,7,9-tetradeoxy-D-glycero-D-galacto-nonulopyranosonate + phosphate (EC 2.5.1.101)
No genes
5,7-diacetamido-3,5,7,9-tetradeoxy-D-glycero-D-galacto-nonulopyranosonate + CTP→CMP-N,N'-diacetyllegionaminate + diphosphate (EC 2.7.7.82)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information