MetaCyc Pathway: pyruvate fermentation to butanol II (engineered) in Rhodosporidium toruloides IFO0880

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Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A
(EC 2.3.1.16; 2.3.1.9)
mRNA_5445 (13813)
mRNA_5687 (14055)
mRNA_6860 (15228)
mRNA_310 (8678)
mRNA_517 (8885)
mRNA_697 (9065)
3-hydroxyacyl-CoA dehydrogenase (in reverse):
acetoacetyl-CoA + NADH + H+→(S)-3-hydroxybutanoyl-CoA + NAD+
(EC 1.1.1.35)
mRNA_2835 (11203)
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
mRNA_2742 (11110)
mRNA_3539 (11907)
mRNA_6437 (14805)
mRNA_7760 (16128)
mRNA_8147 (16515)
Trans-2-enoyl-CoA reductase (NAD(+)) (in reverse):
crotonyl-CoA + NADH + H+→butanoyl-CoA + NAD+
(EC 1.3.1.44)
mRNA_2040 (10408)
mRNA_3718 (12086)
mRNA_4202 (12570)
mRNA_4621 (12989)
mRNA_5702 (14070)
mRNA_7885 (16253)
mRNA_595 (8963)
Butanal dehydrogenase (in reverse):
butanoyl-CoA + NAD(P)H + H+→1-butanal + coenzyme A + NAD(P)+
(EC 1.2.1.57)
No genes
1-butanal + NADH + H+→butan-1-ol + NAD+
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information