MetaCyc Pathway: hopanoid biosynthesis (bacteria) in Rhodosporidium toruloides IFO0880

Add experiment(s):


2 (2E,6E)-farnesyl diphosphate→presqualene diphosphate + diphosphate (EC 2.5.1.103; 2.5.1.21; 2.5.1.96)
mRNA_8223 (16591)
presqualene diphosphate + H2O→hydroxysqualene + diphosphate (EC 4.2.3.156)
No genes
hydroxysqualene + FADH2→squalene + FAD + H+ + H2O (EC 1.17.8.1)
No genes
Squalene--hopene cyclase:
squalene→hop-22(29)-ene (EC 5.4.99.17)
mRNA_872 (9240)
squalene + H2O→tetrahymanol (EC 4.2.1.123)
No genes
squalene + H2O→hopan-22-ol (EC 4.2.1.129)
No genes
hop-22(29)-ene + a reduced unknown two electron carrier + S-adenosyl-L-methionine→adenosyl hopane + an oxidized unknown electron carrier + L-methionine + H+
No genes
tetrahymanol + methylcob(III)alamin + S-adenosyl-L-methionine→2-methyltetrahymanol + 5'-deoxyadenosine + cob(III)alamin + L-methionine
No genes
hopan-22-ol + methylcob(III)alamin + S-adenosyl-L-methionine→2-methyldiplopterol + 5'-deoxyadenosine + cob(III)alamin + L-methionine
No genes
adenosyl hopane + H2O→ribosyl hopane + adenine
No genes
ribosyl hopane→formyl hopane (spontaneous)
No genes
formyl hopane + a reduced unknown two electron carrier→bacteriohopanetetrol + an oxidized unknown electron carrier
No genes
formyl hopane + L-glutamate→aminobacteriohopanetriol + 2-oxoglutarate
No genes
bacteriohopanetetrol + methylcob(III)alamin + S-adenosyl-L-methionine→2-methylbacteriohopanetetrol + 5'-deoxyadenosine + cob(III)alamin + L-methionine
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information