Glucose-1-phosphate thymidylyltransferase:
α-D-glucopyranose 1-phosphate + H+ + dTTP→dTDP-α-D-glucose + diphosphate (EC 2.7.7.24) |
| No genes |
dTDP-glucose 4,6-dehydratase:
dTDP-α-D-glucose→dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H2O (EC 4.2.1.46) |
| mRNA_7050 (15418) |
| dTDP-4-dehydro-6-deoxy-α-D-glucopyranose→dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose + H+ + H2O (EC 4.2.1.159) |
| No genes |
| dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose + H+→dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose (spontaneous) (EC 4.2.1.159) |
| No genes |
| dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose + L-glutamate→dTDP-3-amino-4-dehydro-2,3,6-trideoxy-α-D-glucose + 2-oxoglutarate |
| No genes |
| dTDP-3-amino-4-dehydro-2,3,6-trideoxy-α-D-glucose + 2 S-adenosyl-L-methionine→dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-α-D-glucose + 2 S-adenosyl-L-homocysteine + 2 H+ |
| No genes |
| dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-α-D-glucose→dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-β-L-glucose |
| No genes |
| dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-β-L-glucose + NADPH + H+→dTDP-β-L-megosamine + NADP+ |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information