MetaCyc Pathway: pyrimidine deoxyribonucleotides de novo biosynthesis II in Rhodosporidium toruloides IFO0880
CTP + formate + H+→dCTP + CO2 + H2O (EC 1.1.98.6) |
No genes |
UTP + formate + H+→dUTP + CO2 + H2O (EC 1.1.98.6) |
No genes |
dCTP deaminase: dCTP + H+ + H2O→dUTP + ammonium (EC 3.5.4.13) |
No genes |
dUTP diphosphatase: dUTP + H2O→dUMP + diphosphate + H+ (EC 3.6.1.23; 3.6.1.9) |
mRNA |
mRNA |
Thymidylate synthase: dUMP + a 5,10-methylenetetrahydrofolate→dTMP + a 7,8-dihydrofolate (EC 2.1.1.45) |
mRNA |
mRNA |
T(2)-induced deoxynucleotide kinase: dTMP + ATP→dTDP + ADP (EC 2.7.4.12; 2.7.4.13; 2.7.4.9) |
mRNA |
Nucleoside-diphosphate kinase: dTDP + ATP→dTTP + ADP (EC 2.7.4.6) |
mRNA |
mRNA |
Links:
- Pathway details at MetaCyc
- Fitness data for 7 genes
- All MetaCyc pathways for Rhodosporidium toruloides IFO0880
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information