MetaCyc Pathway: pyrimidine deoxyribonucleotides biosynthesis from CTP in Rhodosporidium toruloides IFO0880
Nucleoside-triphosphatase: CTP + H2O→CDP + H+ + phosphate (EC 3.6.1.15; 3.6.1.5) |
No genes |
Ribonucleoside-diphosphate reductase (in reverse): CDP + a reduced thioredoxin→dCDP + an oxidized thioredoxin + H2O (EC 1.17.4.1) |
mRNA |
mRNA |
mRNA |
Nucleoside-diphosphate kinase: dCDP + ATP→dCTP + ADP (EC 2.7.4.6) |
mRNA |
mRNA |
Apyrase: dCDP + H2O→dCMP + H+ + phosphate (EC 3.6.1.5; 3.6.1.6) |
No genes |
dCMP deaminase: dCMP + H+ + H2O→dUMP + ammonium (EC 3.5.4.12) |
No genes |
Thymidylate synthase: dUMP + a 5,10-methylenetetrahydrofolate→dTMP + a 7,8-dihydrofolate (EC 2.1.1.45) |
mRNA |
mRNA |
T(2)-induced deoxynucleotide kinase: dTMP + ATP→dTDP + ADP (EC 2.7.4.12; 2.7.4.13; 2.7.4.9) |
mRNA |
Nucleoside-diphosphate kinase: dTDP + ATP→dTTP + ADP (EC 2.7.4.6) |
mRNA |
mRNA |
Links:
- Pathway details at MetaCyc
- Fitness data for 8 genes
- All MetaCyc pathways for Rhodosporidium toruloides IFO0880
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information