MetaCyc Pathway: [2Fe-2S] iron-sulfur cluster biosynthesis in Rhodosporidium toruloides IFO0880

Add experiment(s):


Cysteine desulfurase:
an [L-cysteine desulfurase] + L-cysteine→an S-sulfanyl-[L-cysteine desulfurase] + L-alanine (EC 2.8.1.7)
mRNA_5372 (13740)
an S-sulfanyl-[L-cysteine desulfurase] + a [disordered-form [Fe-S] cluster scaffold protein]→an S-sulfanyl-[cysteine desulfurase]-[disordered-form scaffold protein] complex
No genes
an S-sulfanyl-[cysteine desulfurase]-[disordered-form scaffold protein] complex→a [cysteine desulfurase]-S-sulfanyl-[disordered-form scaffold protein] complex
No genes
Cysteine desulfurase:
a [cysteine desulfurase]-S-sulfanyl-[disordered-form scaffold protein] complex + L-cysteine→an S-sulfanyl-[cysteine desulfurase]-S-sulfanyl-[disordered-form scaffold protein] complex + L-alanine (EC 2.8.1.7)
mRNA_5372 (13740)
an S-sulfanyl-[cysteine desulfurase]-S-sulfanyl-[disordered-form scaffold protein] complex→a [cysteine desulfurase]-(S-sulfanyl)2-[disordered-form scaffold protein] complex
No genes
a [cysteine desulfurase]-(S-sulfanyl)2-[disordered-form scaffold protein] complex + 2 Fe3+→a [cysteine desulfurase]-[scaffold protein-(2Fe-2S)] complex
No genes
a [cysteine desulfurase]-[scaffold protein-(2Fe-2S)] complex + an [Fe-S cluster biosynthesis co-chaperone]→an [L-cysteine desulfurase] + a [co-chaperone]-[scaffold protein-(2Fe-2S)] complex
No genes
a [co-chaperone]-[scaffold protein-(2Fe-2S)] complex + an [Fe-S cluster biosynthesis chaperone]-ATP→a [chaperone-ATP]-[co-chaperone]-[scaffold protein-(2Fe-2S)] complex
No genes
a [chaperone-ATP]-[co-chaperone]-[scaffold protein-(2Fe-2S)] complex + an apo-iron-sulfur protein→an [2Fe-2S] cluster protein + a [chaperone-ADP]-[disordered-form scaffold protein] complex + an [Fe-S cluster biosynthesis co-chaperone] + phosphate
No genes
a [chaperone-ADP]-[disordered-form scaffold protein] complex + ATP→an [Fe-S cluster biosynthesis chaperone]-ATP + ADP + a [disordered-form [Fe-S] cluster scaffold protein]
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information