MetaCyc Pathway: 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis II in Rhodosporidium toruloides IFO0880

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Amidophosphoribosyltransferase (in reverse):
5-phospho-α-D-ribose 1-diphosphate + L-glutamine + H2O→5-phospho-β-D-ribosylamine + L-glutamate + diphosphate (EC 2.4.2.14)
mRNA_6932 (15300)
5-phospho-β-D-ribosylamine→2'-hydroxypyridoxol
No genes
2'-hydroxypyridoxol + a reduced unknown two electron carrier→pyridoxine + an oxidized unknown electron carrier + H2O
No genes
Pyridoxal kinase:
pyridoxine + ATP→pyridoxine 5'-phosphate + ADP + H+ (EC 2.7.1.35)
mRNA_6177 (14545)
Pyridoxine 4-dehydrogenase:
pyridoxine + NADP+→pyridoxal + NADPH + H+ (EC 1.1.1.65)
No genes
Pyridoxal 5'-phosphate synthase:
pyridoxine 5'-phosphate + dioxygen→pyridoxal 5'-phosphate + hydrogen peroxide (EC 1.4.3.5)
mRNA_2312 (10680)
Pyridoxal kinase:
pyridoxal + ATP→pyridoxal 5'-phosphate + ADP + H+ (EC 2.7.1.35)
mRNA_6177 (14545)
pyridoxal 5'-phosphate + an [HMP-P synthase]-L-lysine→an [HMP-P synthase]-(PLP-imine)-L-lysine + H+ + H2O
No genes
an [HMP-P synthase]-(PLP-imine)-L-lysine + 2 Fe3+ + [an HMP-P synthase]-L-histidine + 4 H2O→4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe2+ + 3-oxopropanoate + 2 H+ + an [HMP-P synthase]-3-(2-hydroxyacetyl)-L-alanine + an [HMP-P synthase]-L-lysine
mRNA_2779 (11147)
Phosphomethylpyrimidine kinase:
4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP→4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP (EC 2.7.4.7)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information