MetaCyc Pathway: superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis in Rhodosporidium toruloides IFO0880

Add experiment(s):


Glucose-6-phosphate isomerase:
D-glucopyranose 6-phosphate→β-D-fructofuranose 6-phosphate
(EC 5.3.1.9)
mRNA_1221 (9589)
UDP-N-acetylglucosamine 4-epimerase:
UDP-N-acetyl-α-D-glucosamine→UDP-N-acetyl-α-D-galactosamine
(EC 5.1.3.7)
mRNA_601 (8969)
Glutamine--fructose-6-phosphate transaminase (isomerizing):
β-D-fructofuranose 6-phosphate + L-glutamine→D-glucosamine 6-phosphate + L-glutamate
(EC 2.6.1.16)
mRNA_3730 (12098)
mRNA_3731 (12099)
Phosphoglucosamine mutase:
D-glucosamine 6-phosphate→α-D-glucosamine 1-phosphate
(EC 5.4.2.10)
No genes
Glucosamine-1-phosphate N-acetyltransferase:
α-D-glucosamine 1-phosphate + acetyl-CoAN-acetyl-α-D-glucosamine 1-phosphate + coenzyme A + H+
(EC 2.3.1.157)
No genes
UDP-N-acetylglucosamine diphosphorylase:
N-acetyl-α-D-glucosamine 1-phosphate + H+ + UTP→UDP-N-acetyl-α-D-glucosamine + diphosphate
(EC 2.7.7.23)
mRNA_711 (9079)
UDP-N-acetylglucosamine 6-dehydrogenase:
UDP-N-acetyl-α-D-glucosamine + 2 NAD+ + H2O→UDP-N-acetyl-α-D-glucosaminouronate + 2 NADH + 3 H+
(EC 1.1.1.136)
No genes
UDP-N-acetyl-α-D-glucosamine→UDP-2-acetamido-2,6-dideoxy-α-D-xylo-hex-4-ulose + H2O (EC 4.2.1.135)
No genes
UDP-N-acetylglucosamine 4,6-dehydratase (inverting):
UDP-N-acetyl-α-D-glucosamine→UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hex-4-ulose + H2O
(EC 4.2.1.115)
No genes
UDP-N-acetylglucosamine 2-epimerase:
UDP-N-acetyl-α-D-glucosamine→UDP-N-acetyl-α-D-mannosamine
(EC 5.1.3.14)
No genes
UDP-N-acetyl-α-D-glucosaminouronate + NAD+→UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate + NADH + H+ (EC 1.1.1.335)
No genes
UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hex-4-ulose→UDP-2-acetamido-2,6-dideoxy-β-L-lyxo-4-hexulose (EC 1.1.1.367)
No genes
UDP-2-acetamido-2,6-dideoxy-α-D-xylo-hex-4-ulose + NAD(P)H + H+→UDP-N-acetyl-α-D-quinovosamine + NAD(P)+ (EC 1.1.1.426)
No genes
UDP-2-acetamido-2,6-dideoxy-α-D-xylo-hex-4-ulose + NAD(P)H + H+→UDP-N-acetyl-α-D-fucosamine + NAD(P)+
No genes
UDP-N-acetyl-α-D-glucosaminouronate→UDP-N-acetyl-α-D-galactosaminouronate
No genes
UDP-N-acetyl-α-D-mannosamine + 2 NAD+ + H2O→UDP-N-acetyl-α-D-mannosaminuronate + 2 NADH + 3 H+ (EC 1.1.1.336)
No genes
UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate + L-glutamate→UDP-2-acetamido-3-amino-2,3-dideoxy-α-D-glucuronate + 2-oxoglutarate (EC 2.6.1.98)
No genes
UDP-2-acetamido-2,6-dideoxy-β-L-lyxo-4-hexulose + NAD(P)H + H+→UDP-N-acetyl-β-L-pneumosamine + NAD(P)+ (EC 1.1.1.367)
No genes
UDP-2-acetamido-2,6-dideoxy-β-L-lyxo-4-hexulose + NAD(P)H + H+→UDP-N-acetyl-β-L-rhamnosamine + NAD(P)+
No genes
UDP-2-acetamido-3-amino-2,3-dideoxy-α-D-glucuronate + acetyl-CoA→UDP-2,3-diacetamido-2,3-dideoxy-α-D-glucuronate + coenzyme A + H+ (EC 2.3.1.201)
No genes
UDP-N-acetyl-β-L-pneumosamine→UDP-N-acetyl-β-L-fucosamine (EC 5.1.3.28)
No genes
UDP-N-acetyl-β-L-rhamnosamine→UDP-N-acetyl-β-L-quinovosamine
No genes
UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase:
UDP-2,3-diacetamido-2,3-dideoxy-α-D-glucuronate→UDP-2,3-diacetamido-2,3-dideoxy-α-D-mannuronate
(EC 5.1.3.23)
No genes
UDP-N-acetyl-β-L-fucosamine + ammonium→UDP-2,6-dideoxy-2-acetamidino-β-L-galactose + H2O
No genes
UDP-2,3-diacetamido-2,3-dideoxy-α-D-mannuronate + ammonium→UDP-2,3-diacetamidino-2,3-dideoxy-α-D-mannuronate + H2O
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information