MetaCyc Pathway: 10-cis-heptadecenoyl-CoA degradation (yeast) in Rhodosporidium toruloides IFO0880

Add experiment(s):


10-cis-heptadecenoyl-CoA + 2 coenzyme A + 2 NAD+ + 2 dioxygen + 2 H2O→6-cis-tridecenoyl-CoA + 2 acetyl-CoA + 2 hydrogen peroxide + 2 NADH + 2 H+
No genes
Acyl-CoA oxidase:
6-cis-tridecenoyl-CoA + dioxygen→2-trans,6-cis-tridecadienoyl-CoA + hydrogen peroxide
(EC 1.3.3.6)
mRNA_4374 (12742)
mRNA_1332 (9700)
2-trans,6-cis-tridecadienoyl-CoA + H2O→(3R)-hydroxy, 6-cis-tridecenoyl-CoA (EC 4.2.1.119)
No genes
(3R)-hydroxy, 6-cis-tridecenoyl-CoA + NAD+→6-cis, 3-oxo-tridecenoyl-CoA + NADH + H+ (EC 1.1.1.M19)
No genes
Acetyl-CoA C-acyltransferase (in reverse):
6-cis, 3-oxo-tridecenoyl-CoA + coenzyme A→4-cis-undecenoyl-CoA + acetyl-CoA
(EC 2.3.1.16)
mRNA_5445 (13813)
mRNA_5687 (14055)
mRNA_6860 (15228)
mRNA_310 (8678)
mRNA_517 (8885)
mRNA_697 (9065)
Acyl-CoA oxidase:
4-cis-undecenoyl-CoA + dioxygen→(2E,4Z)-undeca-2,4-dienoyl-CoA + hydrogen peroxide
(EC 1.3.3.6)
mRNA_4374 (12742)
mRNA_1332 (9700)
(2E,4Z)-undeca-2,4-dienoyl-CoA + NADPH + H+→(3E)-undec-3-enoyl-CoA + NADP+ (EC 1.3.1.124)
No genes
Dodecenoyl-CoA isomerase:
(3E)-undec-3-enoyl-CoA→(2E)-undec-2-enoyl-CoA
(EC 5.3.3.8)
No genes
(2E)-undec-2-enoyl-CoA + H2O→(3R)-hydroxy-undecanoyl-CoA (EC 4.2.1.119)
No genes
(3R)-hydroxy-undecanoyl-CoA + coenzyme A + NAD+ + dioxygen + H2O→(3R)-hydroxynonanoyl-CoA + acetyl-CoA + hydrogen peroxide + NADH + H+
No genes
(3R)-hydroxynonanoyl-CoA + coenzyme A + NAD+ + dioxygen + H2O→3-hydroxy-heptanoyl-CoA + acetyl-CoA + hydrogen peroxide + NADH + H+
No genes
3-hydroxy-heptanoyl-CoA + coenzyme A + NAD+ + dioxygen + H2O→3-hydroxypentanoyl-CoA + acetyl-CoA + hydrogen peroxide + NADH + H+
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information