MetaCyc Pathway: jasmonic acid biosynthesis in Rhodosporidium toruloides IFO0880

Add experiment(s):


Lipoxygenase:
α-linolenate + dioxygen→13(S)-HPOTE
(EC 1.13.11.12)
No genes
Hydroperoxide dehydratase:
13(S)-HPOTE→(9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate + H2O
(EC 4.2.1.92)
No genes
Allene-oxide cyclase:
(9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate→dinor-12-oxo-phytodienoate
(EC 5.3.99.6)
No genes
12-oxophytodienoate reductase (in reverse):
dinor-12-oxo-phytodienoate + NADPH + H+→8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate + NADP+
(EC 1.3.1.42)
No genes
8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate + ATP + coenzyme A→3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-octanoyl-CoA + AMP + diphosphate
No genes
Acyl-CoA oxidase:
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-octanoyl-CoA + dioxygen→3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA + hydrogen peroxide
(EC 1.3.3.6)
mRNA_4374 (12742)
mRNA_1332 (9700)
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA + H2O→3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA
No genes
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA + NAD+→3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxooctanoyl)-CoA + NADH + H+
No genes
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxooctanoyl)-CoA + coenzyme A→3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-hexanoyl-CoA + acetyl-CoA
(EC 2.3.1.16)
mRNA_5445 (13813)
mRNA_5687 (14055)
mRNA_6860 (15228)
mRNA_310 (8678)
mRNA_517 (8885)
mRNA_697 (9065)
Acyl-CoA oxidase:
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-hexanoyl-CoA + dioxygen→3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA + hydrogen peroxide
(EC 1.3.3.6)
mRNA_4374 (12742)
mRNA_1332 (9700)
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA + H2O→3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA
No genes
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA + NAD+→3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxohexanoyl)-CoA + NADH + H+
No genes
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxohexanoyl)-CoA + coenzyme A→3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-butanoyl-CoA + acetyl-CoA
(EC 2.3.1.16)
mRNA_5445 (13813)
mRNA_5687 (14055)
mRNA_6860 (15228)
mRNA_310 (8678)
mRNA_517 (8885)
mRNA_697 (9065)
Acyl-CoA oxidase:
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-butanoyl-CoA + dioxygen→3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA + hydrogen peroxide
(EC 1.3.3.6)
mRNA_4374 (12742)
mRNA_1332 (9700)
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA + H2O→3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA
No genes
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA + NAD+→3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxobutanoyl)-CoA + NADH + H+
No genes
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxobutanoyl)-CoA + coenzyme A→(+)-7-epi-jasmonoyl-CoA + acetyl-CoA
(EC 2.3.1.16)
mRNA_5445 (13813)
mRNA_5687 (14055)
mRNA_6860 (15228)
mRNA_310 (8678)
mRNA_517 (8885)
mRNA_697 (9065)
Acyl-CoA hydrolase:
(+)-7-epi-jasmonoyl-CoA + H2O→(+)-7-epi-jasmonate + coenzyme A + H+
(EC 3.1.2.20)
No genes
(+)-7-epi-jasmonate→(-)-jasmonate (spontaneous)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information