MetaCyc Pathway: thiamine phosphate formation from pyrithiamine and oxythiamine (yeast) in Rhodosporidium toruloides IFO0880

Add experiment(s):


pyrithiamine + an oxidized unknown electron carrier + H2O→4-amino-2-methyl-5-pyrimidinemethanol + 2-(2-methylpyridin-3-yl)ethanol + a reduced unknown two electron carrier
No genes
oxythiamine + H2O→5-(2-hydroxyethyl)-4-methylthiazole + 5-(hydroxymethyl)-2-methyl-4(1H)-pyrimidinone + H+
No genes
Hydroxymethylpyrimidine kinase:
4-amino-2-methyl-5-pyrimidinemethanol + ATP→4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ADP + H+ (EC 2.7.1.49)
No genes
Hydroxyethylthiazole kinase:
5-(2-hydroxyethyl)-4-methylthiazole + ATP→4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ (EC 2.7.1.50)
mRNA_7845 (16213)
Phosphomethylpyrimidine kinase:
4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP→4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP (EC 2.7.4.7)
No genes
Thiamine-phosphate diphosphorylase:
4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)thiazole + H+→thiamine phosphate + diphosphate (EC 2.5.1.3)
mRNA_7845 (16213)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information