MetaCyc Pathway: superpathway of anaerobic energy metabolism (invertebrates) in Rhodosporidium toruloides IFO0880

Add experiment(s):


Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + GDP→oxaloacetate + GTP (EC 4.1.1.32)
No genes
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
mRNA_2701 (11069)
mRNA_4634 (13002)
Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + IDP→oxaloacetate + ITP (EC 4.1.1.32)
No genes
Alanine transaminase (in reverse):
pyruvate + L-glutamate→2-oxoglutarate + L-alanine (EC 2.6.1.2)
mRNA_1267 (9635)
Alanine racemase:
L-alanine→D-alanine (EC 5.1.1.1)
No genes
Aspartate transaminase:
2-oxoglutarate + L-aspartate→L-glutamate + oxaloacetate (EC 2.6.1.1)
mRNA_5562 (13930)
mRNA_5913 (14281)
mRNA_7697 (16065)
mRNA_172 (8540)
mRNA_568 (8936)
mRNA_1267 (9635)
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
mRNA_2246 (10614)
mRNA_2810 (11178)
mRNA_4393 (12761)
mRNA_5549 (13917)
Malate dehydrogenase (oxaloacetate-decarboxylating):
(S)-malate + NAD+→pyruvate + CO2 + NADH (EC 1.1.1.38)
mRNA_4393 (12761)
mRNA_5549 (13917)
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
mRNA_5633 (14001)
pyruvate + coenzyme A + NAD+→acetyl-CoA + CO2 + NADH (EC 1.2.1.104)
mRNA_5262 (13630)
mRNA_5354 (13722)
mRNA_5580 (13948)
mRNA_5758 (14126)
fumarate[in] + a rhodoquinol→succinate[in] + a rhodoquinone (EC 1.3.5.4)
No genes
acetyl-CoA + succinate→acetate + succinyl-CoA (EC 2.8.3.18)
No genes
succinate + propanoyl-CoA→succinyl-CoA + propanoate (EC 2.8.3.M4)
No genes
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
No genes
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
mRNA_7599 (15967)
mRNA_7776 (16144)
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
No genes
Propionyl-CoA carboxylase (in reverse):
(S)-methylmalonyl-CoA + ADP + H+ + phosphate→propanoyl-CoA + ATP + hydrogencarbonate (EC 6.4.1.3)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information