MetaCyc Pathway: bacilysin biosynthesis in Rhodosporidium toruloides IFO0880

Add experiment(s):


Chorismate mutase:
chorismate→prephenate
(EC 5.4.99.5)
mRNA_1336 (9704)
prephenate + H+→3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2 (EC 4.1.1.100)
No genes
3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate→3-[(1E,4R)-4-hydroxycyclohex-2-en-1-ylidene]-2-oxopropanoate (EC 5.3.3.19)
No genes
3-[(1E,4R)-4-hydroxycyclohex-2-en-1-ylidene]-2-oxopropanoate + a reduced unknown two electron carrier + dioxygen→3-[(2E,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate + an oxidized unknown electron carrier + H2O
No genes
3-[(2E,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate + NAD(P)H + H+→3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + NAD(P)+ (EC 1.3.1.aa)
No genes
3-[(2E,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate→3-[(2Z,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate (EC 5.3.3.19)
No genes
3-[(2Z,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate + NAD(P)H + H+→3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + NAD(P)+ (EC 1.3.1.aa)
No genes
3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + L-phenylalanine→L-dihydroanticapsin + 3-phenyl-2-oxopropanoate
No genes
L-dihydroanticapsin + NAD+→L-anticapsin + NADH + H+ (EC 1.1.1.385)
No genes
L-anticapsin[cytosol] + L-alanine[cytosol] + ATP[cytosol]→bacilysin[cytosol] + ADP[cytosol] + H+[cytosol] + phosphate[cytosol] (EC 6.3.2.49)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information