MetaCyc Pathway: CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis in Rhodosporidium toruloides IFO0880

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Arabinose-5-phosphate isomerase (in reverse):
D-ribulose 5-phosphate→aldehydo-D-arabinose 5-phosphate (EC 5.3.1.13)
mRNA_8117 (16485)
aldehydo-D-arabinose 5-phosphate→D-arabinofuranose 5-phosphate (spontaneous)
No genes
3-deoxy-8-phosphooctulonate synthase:
D-arabinofuranose 5-phosphate + phosphoenolpyruvate + H2O→3-deoxy-D-manno-octulosonate 8-phosphate + phosphate (EC 2.5.1.55)
No genes
3-deoxy-manno-octulosonate-8-phosphatase:
3-deoxy-D-manno-octulosonate 8-phosphate + H2O→3-deoxy-α-D-manno-2-octulosonate + phosphate (EC 3.1.3.45)
No genes
3-deoxy-α-D-manno-2-octulosonate + dioxygen→3,8-dideoxy-8-oxo-α-D-manno-octulosonate + hydrogen peroxide (EC 1.1.3.48)
No genes
3,8-dideoxy-8-oxo-α-D-manno-octulosonate + L-glutamate→8-amino-3,8-dideoxy-α-D-manno-octulosonate + 2-oxoglutarate (EC 2.6.1.109)
No genes
8-amino-3,8-dideoxy-α-D-manno-octulosonate + CTP→CMP-8-amino-3,8-dideoxy-α-D-manno-octulosonate + diphosphate (EC 2.7.7.90)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information