MetaCyc Pathway: 2,5-xylenol and 3,5-xylenol degradation in Rhodosporidium toruloides IFO0880

Add experiment(s):


2,5-xylenol + NADH + dioxygen + H+→5-(hydroxymethyl)-2-methylphenol + NAD+ + H2O (EC 1.14.13.M67)
No genes
3,5-xylenol + NADH + dioxygen + H+→3-(hydroxymethyl)-5-methylphenol + NAD+ + H2O (EC 1.14.13.M67)
No genes
Aryl-alcohol dehydrogenase:
5-(hydroxymethyl)-2-methylphenol + NAD+→3-hydroxy-4-methylbenzaldehyde + NADH + H+
(EC 1.1.1.90)
mRNA_1713 (10081)
mRNA_5059 (13427)
Aryl-alcohol dehydrogenase:
3-(hydroxymethyl)-5-methylphenol + NAD+→3-hydroxy-5-methylbenzaldehyde + NADH + H+
(EC 1.1.1.90)
mRNA_1713 (10081)
mRNA_5059 (13427)
Benzaldehyde dehydrogenase (NADP(+)):
3-hydroxy-4-methylbenzaldehyde + NADP+ + H2O→3-hydroxy-4-methyl-benzoate + NADPH + 2 H+
(EC 1.2.1.7)
No genes
Benzaldehyde dehydrogenase (NADP(+)):
3-hydroxy-5-methylbenzaldehyde + NADP+ + H2O→3-hydroxy-5-methyl-benzoate + NADPH + 2 H+
(EC 1.2.1.7)
No genes
3-hydroxybenzoate 6-monooxygenase:
3-hydroxy-4-methyl-benzoate + NADH + dioxygen + H+→4-methylgentisate + NAD+ + H2O
(EC 1.14.13.24)
No genes
3-hydroxybenzoate 6-monooxygenase:
3-hydroxy-5-methyl-benzoate + NADH + dioxygen + H+→3-methylgentisate + NAD+ + H2O
(EC 1.14.13.24)
No genes
Gentisate 1,2-dioxygenase:
3-methylgentisate + dioxygen→(2E)-2-methyl-4,6-dioxohept-2-enedioate + H+
(EC 1.13.11.4)
No genes
Gentisate 1,2-dioxygenase:
4-methylgentisate + dioxygen→(2E)-3-methyl-4,6-dioxohept-2-enedioate + H+
(EC 1.13.11.4)
No genes
(2E)-2-methyl-4,6-dioxohept-2-enedioate + H2O→citraconate + H+ + pyruvate (EC 3.7.1.23)
No genes
(2E)-3-methyl-4,6-dioxohept-2-enedioate + H2O→citraconate + H+ + pyruvate (EC 3.7.1.23)
No genes
(R)-2-methylmalate dehydratase (in reverse):
citraconate + H2O→(R)-citramalate
(EC 4.2.1.35)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information