MetaCyc Pathway: L-leucine degradation IV (reductive Stickland reaction) in Rhodosporidium toruloides IFO0880

Add experiment(s):


Branched-chain-amino-acid transaminase:
L-leucine + 2-oxoglutarate→4-methyl-2-oxopentanoate + L-glutamate (EC 2.6.1.42; 2.6.1.6)
mRNA_5646 (14014)
mRNA_6242 (14610)
mRNA_6485 (14853)
4-methyl-2-oxopentanoate + NADH + H+→(R)-2-hydroxy-4-methylpentanoate + NAD+ (EC 1.1.1.345)
No genes
(R)-2-hydroxy-4-methylpentanoate + 4-methylpentanoyl-CoA→(R)-2-hydroxy-4-methylpentanoyl-CoA + 4-methylpentanoate (EC 2.8.3.24)
No genes
(R)-2-hydroxy-4-methylpentanoyl-CoA→4-methylpent-2-enoyl-CoA + H2O (EC 4.2.1.157)
No genes
Trans-2-enoyl-CoA reductase (NAD(+)) (in reverse):
4-methylpent-2-enoyl-CoA + NADH + H+→4-methylpentanoyl-CoA + NAD+ (EC 1.3.1.44)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information