MetaCyc Pathway: plasmalogen biosynthesis in Rhodosporidium toruloides IFO0880

Add experiment(s):


Glycerone-phosphate O-acyltransferase:
a long-chain fatty acyl-CoA + glycerone phosphate→a 1-long-chain acyl-glycerone 3-phosphate + coenzyme A (EC 2.3.1.42)
No genes
Choline kinase:
choline + ATP→phosphocholine + ADP + H+ (EC 2.7.1.32)
No genes
L-serine + H+→ethanolamine + CO2
No genes
a long-chain fatty acyl-CoA + 2 NADPH + 2 H+→a long-chain fatty alcohol + coenzyme A + 2 NADP+ (EC 1.2.1.84)
No genes
Choline-phosphate cytidylyltransferase:
phosphocholine + CTP + H+→CDP-choline + diphosphate (EC 2.7.7.15)
mRNA_2172 (10540)
Alkylglycerone-phosphate synthase:
a 1-long-chain acyl-glycerone 3-phosphate + a long-chain fatty alcohol→a 1-alkyl-glycerone 3-phosphate + a long-chain fatty acid + H+ (EC 2.5.1.26)
No genes
Ethanolamine kinase:
ethanolamine + ATP→O-phosphoethanolamine + ADP + H+ (EC 2.7.1.82)
No genes
Ethanolamine-phosphate cytidylyltransferase:
O-phosphoethanolamine + CTP + H+→CDP-ethanolamine + diphosphate (EC 2.7.7.14)
No genes
Acylglycerone-phosphate reductase (in reverse):
a 1-alkyl-glycerone 3-phosphate + NADPH + H+→a 1-alkyl-sn-glycerol 3-phosphate + NADP+ (EC 1.1.1.101)
No genes
1-acylglycerol-3-phosphate O-acyltransferase:
a 1-alkyl-sn-glycerol 3-phosphate + an acyl-CoA→a 2-acyl-1-alkyl-sn-glycerol 3-phosphate + coenzyme A (EC 2.3.1.51)
mRNA_2059 (10427)
Phosphatidate phosphatase:
a 2-acyl-1-alkyl-sn-glycerol 3-phosphate + H2O→a 2-acyl-1-alkyl-sn-glycerol + phosphate (EC 3.1.3.4)
No genes
Ethanolaminephosphotransferase:
a 2-acyl-1-alkyl-sn-glycerol + CDP-ethanolamine→a plasmanylethanolamine + CMP + H+ (EC 2.7.8.1)
mRNA_720 (9088)
Diacylglycerol cholinephosphotransferase:
a 2-acyl-1-alkyl-sn-glycerol + CDP-choline→a plasmanylcholine + CMP + H+ (EC 2.7.8.2)
mRNA_720 (9088)
a plasmanylethanolamine + 2 a ferrocytochrome b5 + dioxygen + 2 H+→a plasmenylethanolamine + 2 a ferricytochrome b5 + 2 H2O (EC 1.14.19.77)
No genes
Phospholipase C:
a plasmenylethanolamine + H2O→O-phosphoethanolamine + a 2-acyl-1-Z-alk-1-enyl-sn-glycerol + H+ (EC 3.1.4.3)
No genes
1-alkenyl-2-acylglycerol choline phosphotransferase:
a 2-acyl-1-Z-alk-1-enyl-sn-glycerol + CDP-choline→a plasmenylcholine + CMP + H+ (EC 2.7.8.22)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information