MetaCyc Pathway: tRNA-uridine 2-thiolation (mammalian mitochondria) in Rhodosporidium toruloides IFO0880

Add experiment(s):


a uridine in tRNA + an oxidized unknown electron carrier + GTP + a 5,10-methylenetetrahydrofolate + taurine + H2O→a 5-taurinomethyluridine in tRNA + a 7,8-dihydrofolate + a reduced unknown two electron carrier + GDP + 2 H+ + phosphate
No genes
Cysteine desulfurase:
L-cysteine + an [L-cysteine desulfurase]-L-cysteine→an [L-cysteine desulfurase]-S-sulfanyl-L-cysteine + L-alanine
(EC 2.8.1.7)
mRNA_5372 (13740)
an [L-cysteine desulfurase]-S-sulfanyl-L-cysteine + a [3-mercaptopyruvate sulfurtransferase]-L-cysteine→a [3-mercaptopyruvate sulfurtransferase]-S-sulfanyl-L-cysteine + an [L-cysteine desulfurase]-L-cysteine
No genes
a [3-mercaptopyruvate sulfurtransferase]-S-sulfanyl-L-cysteine + a 5-taurinomethyluridine in tRNA + ATP + a reduced unknown two electron carrier→a 5-taurinomethyl-2-thiouridine in tRNA + AMP + an oxidized unknown electron carrier + diphosphate + H+ + a [3-mercaptopyruvate sulfurtransferase]-L-cysteine (EC 2.8.1.14)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information