MetaCyc Pathway: protein NEDDylation in Rhodosporidium toruloides IFO0880

Add experiment(s):


a [NEDD8] C-terminal glycine + ATP + an [E1 NEDD8-activating enzyme]-L-cysteine→an [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + AMP + diphosphate (EC 6.2.1.64)
mRNA_579 (8947)
an [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + an [E2 NEDD8-conjugating enzyme]-L-cysteine→an [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + an [E1 NEDD8-activating enzyme]-L-cysteine (EC 2.3.2.34)
mRNA_7323 (15691)
an [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + a [cullin]-L-lysine→a [cullin]-N6-[NEDD8-protein]-yl-L-lysine + an [E2 NEDD8-conjugating enzyme]-L-cysteine + H+ (EC 2.3.2.32)
mRNA_8115 (16483)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information