MetaCyc Pathway: firefly bioluminescence in Rhodosporidium toruloides IFO0880

Add experiment(s):


Beta-glucosidase:
arbutin + H2O→hydroquinone + D-glucopyranose (EC 3.2.1.21)
mRNA_5118 (13486)
mRNA_8348 (16716)
mRNA_8349 (16717)
mRNA_160 (8528)
mRNA_1271 (9639)
Monophenol monooxygenase:
2 hydroquinone + dioxygen→2 1,4-benzoquinone + 2 H2O (EC 1.14.18.1)
No genes
1,4-benzoquinone + L-cysteine→2-amino-3-[(2,5-dihydroxyphenyl)sulfanyl]propanoate
No genes
2-amino-3-[(2,5-dihydroxyphenyl)sulfanyl]propanoate + 4 an oxidized unknown electron carrier + L-cysteine→L-firefly luciferin + CO2 + 4 a reduced unknown two electron carrier + H+ + H2O
No genes
L-firefly luciferin + ATP + H+→(L-firefly luciferyl)adenylate + diphosphate (EC 6.2.1.52)
No genes
(L-firefly luciferyl)adenylate + coenzyme A→L-firefly luciferyl-CoA + AMP + H+ (EC 6.2.1.52)
No genes
L-firefly luciferyl-CoA→D-firefly luciferyl-CoA (EC 5.1.99.M3)
No genes
Acyl-CoA hydrolase:
D-firefly luciferyl-CoA + H2O→D-firefly luciferin + coenzyme A + H+ (EC 3.1.2.20)
No genes
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing):
D-firefly luciferin + ATP + H+→(D-firefly luciferyl)adenylate + diphosphate (EC 1.13.12.7)
No genes
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing):
(D-firefly luciferyl)adenylate + dioxygen→firefly oxyluciferin-dioxetanone + AMP + hν + H+ (EC 1.13.12.7)
No genes
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing):
firefly oxyluciferin-dioxetanone→excited state firefly oxyluciferin + CO2 (EC 1.13.12.7)
No genes
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing):
excited state firefly oxyluciferin→ground state firefly oxyluciferin + hν (spontaneous) (EC 1.13.12.7)
No genes
ground state firefly oxyluciferin + a reduced unknown two electron carrier + H2O→2-cyano-6-hydroxybenzothiazole + an oxidized unknown electron carrier + H+ + thioglycolate (EC 3.12.1.M1)
No genes
2-cyano-6-hydroxybenzothiazole + an oxidized unknown electron carrier + L-cysteine→L-firefly luciferin + ammonium + a reduced unknown two electron carrier
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information