MetaCyc Pathway: Entner-Doudoroff pathway I in Rhodosporidium toruloides IFO0880

Add experiment(s):


Glucose-6-phosphate dehydrogenase:
D-glucopyranose 6-phosphate + NADP+→6-phospho D-glucono-1,5-lactone + NADPH + H+
(EC 1.1.1.49)
mRNA_1632 (10000)
6-phosphogluconolactonase:
6-phospho D-glucono-1,5-lactone + H2O→D-gluconate 6-phosphate + H+
(EC 3.1.1.31)
mRNA_6131 (14499)
Phosphogluconate dehydratase:
D-gluconate 6-phosphate→2-dehydro-3-deoxy-D-gluconate 6-phosphate + H2O
(EC 4.2.1.12)
No genes
2-dehydro-3-deoxy-phosphogluconate aldolase:
2-dehydro-3-deoxy-D-gluconate 6-phosphate→D-glyceraldehyde 3-phosphate + pyruvate
(EC 4.1.2.14; 4.1.2.55)
No genes
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+
(EC 1.2.1.12)
mRNA_2245 (10613)
mRNA_3311 (11679)
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP
(EC 2.7.2.3)
mRNA_7353 (15721)
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
No genes
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O
(EC 4.2.1.11)
mRNA_4451 (12819)
mRNA_8034 (16402)
mRNA_669 (9037)
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP
(EC 2.7.1.40)
mRNA_2701 (11069)
mRNA_4634 (13002)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information