3-beta-hydroxy-Delta(5)-steroid dehydrogenase:
cholesterol + NAD+→cholest-5-en-3-one + NADH + H+ (EC 1.1.1.145) |
| No genes |
Cholesterol oxidase:
cholest-5-en-3-one→cholest-4-en-3-one (EC 1.1.3.6; 5.3.3.1) |
| No genes |
| cholest-4-en-3-one + an oxidized unknown electron carrier + H2O→25-hydroxycholest-4-en-3-one + a reduced unknown two electron carrier (EC 1.17.99.10) |
| No genes |
| 25-hydroxycholest-4-en-3-one→(25R)-26-hydroxycholest-4-en-3-one |
| No genes |
| (25R)-26-hydroxycholest-4-en-3-one + an oxidized unknown electron carrier→(25R)-26-oxocholest-4-en-3-one + a reduced unknown two electron carrier |
| No genes |
| (25R)-26-oxocholest-4-en-3-one + NAD+ + H2O→(25R)-3-oxocholest-4-en-26-oate + NADH + 2 H+ |
| No genes |
| (25R)-3-oxocholest-4-en-26-oate[out]→(25R)-3-oxocholest-4-en-26-oate[in] |
| No genes |
| (25R)-3-oxocholest-4-en-26-oate + ATP + coenzyme A→(25R)-3-oxocholest-4-en-26-oyl-CoA + AMP + diphosphate (EC 6.2.1.42) |
| No genes |
Alpha-methylacyl-CoA racemase (in reverse):
(25R)-3-oxocholest-4-en-26-oyl-CoA→(25S)-3-oxocholest-4-en-26-oyl-CoA (EC 5.1.99.4) |
| mRNA_248 (8616) |
| (25S)-3-oxocholest-4-en-26-oyl-CoA + an oxidized unknown electron carrier→3-oxocholest-4,24-dien-26-oyl-CoA + a reduced unknown two electron carrier |
| No genes |
| 3-oxocholest-4,24-dien-26-oyl-CoA + H2O→24-hydroxy-3-oxocholest-4-en-26-oyl-CoA |
| No genes |
| 24-hydroxy-3-oxocholest-4-en-26-oyl-CoA→22-oxocholest-4-en-3-one + propanoyl-CoA |
| No genes |
| 22-oxocholest-4-en-3-one + NAD+ + H2O→3-oxochol-4-en-24-oate + NADH + 2 H+ |
| No genes |
| 3-oxochol-4-en-24-oate + ATP + coenzyme A→3-oxochol-4-en-24-oyl-CoA + AMP + diphosphate |
| No genes |
| 3-oxochol-4-en-24-oyl-CoA + an oxidized unknown electron carrier→3-oxochol-4,22-dien-24-oyl-CoA + a reduced unknown two electron carrier |
| No genes |
| 3-oxochol-4,22-dien-24-oyl-CoA + H2O→22-hydroxy-3-oxochol-4-en-24-oyl-CoA |
| No genes |
| 22-hydroxy-3-oxochol-4-en-24-oyl-CoA→3,23-dioxo-23,24-bisnorchol-4-ene + acetyl-CoA |
| No genes |
| 3,23-dioxo-23,24-bisnorchol-4-ene + NAD+ + H2O→3-oxo-23,24-bisnorchol-4-en-22-oate + NADH + 2 H+ |
| No genes |
| 3-oxo-23,24-bisnorchol-4-en-22-oate + ATP + coenzyme A→3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA + AMP + diphosphate |
| No genes |
| 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA + an oxidized unknown electron carrier→3-oxo-23,24-bisnorchol-4,17(20)-dien-22-oyl-CoA + a reduced unknown two electron carrier |
| No genes |
| 3-oxo-23,24-bisnorchol-4,17(20)-dien-22-oyl-CoA + H2O→17-hydroxy-3-oxo-4-pregnane-20-carboxyl-CoA |
| No genes |
| 17-hydroxy-3-oxo-4-pregnane-20-carboxyl-CoA→androstenedione + propanoyl-CoA |
| No genes |
3-oxosteroid 1-dehydrogenase:
androstenedione + an oxidized unknown electron carrier→androsta-1,4-diene-3,17-dione + a reduced unknown two electron carrier (EC 1.3.99.4) |
| No genes |
3-oxo-5-alpha-steroid 4-dehydrogenase (in reverse):
androsta-1,4-diene-3,17-dione + a reduced unknown two electron carrier→androsta-1-ene-3,17-dione + an oxidized unknown electron carrier (EC 1.3.99.5) |
| No genes |
| androsta-1-ene-3,17-dione + H2O→1-hydroxyandrostan-3,17-dione (EC 1.17.99.11) |
| No genes |
| 1-hydroxyandrostan-3,17-dione + an oxidized unknown electron carrier→androstan-1,3,17-trione + a reduced unknown two electron carrier (EC 1.17.99.11) |
| No genes |
| androstan-1,3,17-trione + H2O→1,17-dioxo-2,3-seco-androstan-3-oate + H+ |
| No genes |
| 1,17-dioxo-2,3-seco-androstan-3-oate + ATP + coenzyme A→1,17-dioxo-2,3-seco-androstan-3-oyl-CoA + AMP + diphosphate |
| No genes |
| 1,17-dioxo-2,3-seco-androstan-3-oyl-CoA + an oxidized unknown electron carrier→1,17-dioxo-2,3-seco-androsta-4-en-3-oyl-CoA + a reduced unknown two electron carrier |
| No genes |
| 1,17-dioxo-2,3-seco-androsta-4-en-3-oyl-CoA + H2O→4-hydroxy-1,17-dioxo-2,3-seco-androstan-3-oyl-CoA |
| No genes |
| 4-hydroxy-1,17-dioxo-2,3-seco-androstan-3-oyl-CoA→2,5-seco-3,4-dinorandrost-1,5,17-trione + acetyl-CoA |
| No genes |
| 2,5-seco-3,4-dinorandrost-1,5,17-trione→3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate |
| No genes |
| 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + coenzyme A→3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate (EC 6.2.1.41) |
| No genes |
3-beta-hydroxy-Delta(5)-steroid dehydrogenase (in reverse):
3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + NADPH + H+→3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]propanoyl-CoA + NADP+ (EC 1.1.1.145) |
| No genes |
| 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]propanoyl-CoA + an oxidized unknown electron carrier→(2E)-3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]prop-2-enoyl-CoA + a reduced unknown two electron carrier |
| No genes |
| (2E)-3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]prop-2-enoyl-CoA + H2O→3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-hydroxypropanoyl-CoA |
| No genes |
3-hydroxyacyl-CoA dehydrogenase:
3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-hydroxypropanoyl-CoA + NAD+→3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA + NADH + H+ (EC 1.1.1.35) |
| mRNA_2835 (11203) |
| 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA + H2O→3aα-H-4α-carboxy-5-hydroxy-7aβ-methylhexahydro-1-indanone + acetyl-CoA + H+ |
| No genes |
| 3aα-H-4α-carboxy-5-hydroxy-7aβ-methylhexahydro-1-indanone + ATP + coenzyme A→(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxyl-CoA + AMP + diphosphate |
| No genes |
| (3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxyl-CoA + NAD+→(5R,7aS)-5-hydroxy-7a-methyl-1-oxo-3,5,6,7-tetrahydro-2H-indene-4-carboxyl-CoA + NADH + H+ |
| No genes |
| (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-3,5,6,7-tetrahydro-2H-indene-4-carboxyl-CoA + NAD+→(5R,7aS)-7a-methyl-1,5-dioxo-3,5,6,7-tetrahydro-2H-indene-4-carboxyl-CoA + NADH + H+ |
| No genes |
| (5R,7aS)-7a-methyl-1,5-dioxo-3,5,6,7-tetrahydro-2H-indene-4-carboxyl-CoA + H2O→(3R)-2-(2-carboxyethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA + H+ |
| No genes |
| (3R)-2-(2-carboxyethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA + H2O→9-carboxy-6-methyl-3,7-dioxononanoyl-CoA |
| No genes |
Acetyl-CoA C-acyltransferase (in reverse):
9-carboxy-6-methyl-3,7-dioxononanoyl-CoA + coenzyme A→7-carboxy-4-methyl-5-oxoheptanoyl-CoA + acetyl-CoA (EC 2.3.1.16) |
| mRNA_5445 (13813) |
| mRNA_5687 (14055) |
| mRNA_6860 (15228) |
| mRNA_310 (8678) |
| mRNA_517 (8885) |
| mRNA_697 (9065) |
| 7-carboxy-4-methyl-5-oxoheptanoyl-CoA + an oxidized electron-transfer flavoprotein + H+→(2E)-7-carboxy-4-methyl-5-oxohept-2-enoyl-CoA + a reduced electron-transfer flavoprotein |
| No genes |
| (2E)-7-carboxy-4-methyl-5-oxohept-2-enoyl-CoA + H2O→(3R)-7-carboxy-3-hydroxy-4-methyl-5-oxoheptanoyl-CoA (EC 4.2.1.119) |
| No genes |
3-hydroxyacyl-CoA dehydrogenase:
(3R)-7-carboxy-3-hydroxy-4-methyl-5-oxoheptanoyl-CoA + NAD+→7-carboxy-4-methyl-3,5-dioxoheptanoyl-CoA + NADH + H+ (EC 1.1.1.35) |
| mRNA_2835 (11203) |
Acetyl-CoA C-acyltransferase (in reverse):
7-carboxy-4-methyl-3,5-dioxoheptanoyl-CoA + coenzyme A→5-carboxy-2-methyl-3-oxopentanoyl-CoA + acetyl-CoA (EC 2.3.1.16) |
| mRNA_5445 (13813) |
| mRNA_5687 (14055) |
| mRNA_6860 (15228) |
| mRNA_310 (8678) |
| mRNA_517 (8885) |
| mRNA_697 (9065) |
| 5-carboxy-2-methyl-3-oxopentanoyl-CoA + coenzyme A→succinyl-CoA + propanoyl-CoA |
| No genes |