Sterol 24-C-methyltransferase:
cycloartenol + S-adenosyl-L-methionine→24-methylenecycloartanol + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.41) |
| mRNA_4692 (13060) |
| 24-methylenecycloartanol + 6 a ferrocytochrome b5 + 3 dioxygen + 5 H+→4α-carboxy-4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol + 6 a ferricytochrome b5 + 4 H2O (EC 1.14.18.10) |
| No genes |
| 4α-carboxy-4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol + NAD+→cycloeucalenone + CO2 + NADH (EC 1.1.1.418) |
| No genes |
3-keto-steroid reductase (in reverse):
cycloeucalenone + NADPH + H+→cycloeucalenol + NADP+ (EC 1.1.1.270) |
| No genes |
Cycloeucalenol cycloisomerase:
cycloeucalenol→obtusifoliol (EC 5.5.1.9) |
| No genes |
| obtusifoliol + 3 dioxygen + 3 a reduced [NADPH-hemoprotein reductase]→4α-methyl-5α-ergosta-8,14,24(28)-trien-3β-ol + formate + 3 an oxidized [NADPH-hemoprotein reductase] + H+ + 4 H2O (EC 1.14.14.154) |
| No genes |
Delta(14)-sterol reductase (in reverse):
4α-methyl-5α-ergosta-8,14,24(28)-trien-3β-ol + NADPH + H+→4α-methylfecosterol + NADP+ (EC 1.3.1.70) |
| No genes |
Cholestenol Delta-isomerase (in reverse):
4α-methylfecosterol→24-methylidenelophenol (EC 5.3.3.5) |
| No genes |
| 24-methylidenelophenol + 6 a ferrocytochrome b5 + 3 dioxygen + 5 H+→4α-carboxy-ergosta-7,24(241)-dien-3β-ol + 6 a ferricytochrome b5 + 4 H2O (EC 1.14.18.11) |
| No genes |
| 24-methylidenelophenol + S-adenosyl-L-methionine→(24E)-24-ethylidenelophenol + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.M86) |
| No genes |
| 4α-carboxy-ergosta-7,24(241)-dien-3β-ol + NAD+→episterone + CO2 + NADH (EC 1.1.1.418) |
| No genes |
| (24E)-24-ethylidenelophenol + 6 a ferrocytochrome b5 + 3 dioxygen + 5 H+→(24E)-4α-carboxy-stigmasta-7,24(241)-dien-3β-ol + 6 a ferricytochrome b5 + 4 H2O (EC 1.14.18.11) |
| No genes |
| episterone + NADPH + H+→episterol + NADP+ |
| No genes |
| (24E)-4α-carboxy-stigmasta-7,24(241)-dien-3β-ol + NAD+→isoavenastenone + CO2 + NADH (EC 1.1.1.418) |
| No genes |
3-keto-steroid reductase (in reverse):
isoavenastenone + NADPH + H+→isoavenasterol + NADP+ (EC 1.1.1.270) |
| No genes |
| episterol + 2 a ferrocytochrome b5 + dioxygen + 2 H+→ergosta-5,7,24(28)-trien-3β-ol + 2 a ferricytochrome b5 + 2 H2O (EC 1.14.19.20) |
| No genes |
| isoavenasterol + 2 a ferrocytochrome b5 + dioxygen + 2 H+→5-dehydroisoavenasterol + 2 a ferricytochrome b5 + 2 H2O (EC 1.14.19.20) |
| No genes |
7-dehydrocholesterol reductase (in reverse):
ergosta-5,7,24(28)-trien-3β-ol + NADPH + H+→24-methylenecholesterol + NADP+ (EC 1.3.1.21) |
| No genes |
7-dehydrocholesterol reductase (in reverse):
5-dehydroisoavenasterol + NADPH + H+→fucosterol + NADP+ (EC 1.3.1.21) |
| No genes |
Delta(24(24(1)))-sterol reductase (in reverse):
24-methylenecholesterol + NADPH + H+→24-epi-campesterol + NADP+ (EC 1.3.1.71) |
| mRNA_2613 (10981) |
Delta(24(24(1)))-sterol reductase (in reverse):
fucosterol + NADPH + H+→clionasterol + NADP+ (EC 1.3.1.71) |
| mRNA_2613 (10981) |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information