MetaCyc Pathway: cremeomycin biosynthesis in Rhodosporidium toruloides IFO0880

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Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP (EC 2.7.2.4)
mRNA_6294 (14662)
mRNA_8370 (16738)
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate (EC 1.2.1.11)
mRNA_1962 (10330)
L-aspartate 4-semialdehyde + glycerone phosphate→2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate (EC 4.1.2.56)
No genes
2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate→3-amino-4-hydroxybenzoate + H+ + phosphate + 2 H2O (EC 4.1.99.20)
No genes
3-amino-4-hydroxybenzoate + NADPH + dioxygen + H+→3-amino-2,4-dihydroxybenzoate + NADP+ + H2O (EC 1.14.13.fa)
No genes
3-amino-2,4-dihydroxybenzoate + S-adenosyl-L-methionine→3-amino-2-hydroxy-4-methoxybenzoate + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.hu)
No genes
3-amino-2-hydroxy-4-methoxybenzoate + nitrite + ATP→cremeomycin + AMP + diphosphate + H2O (EC 6.7.1.a)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information