Phenylacetate--CoA ligase:
phenylacetate + ATP + coenzyme A→phenylacetyl-CoA + AMP + diphosphate (EC 6.2.1.30) |
| No genes |
| phenylacetyl-CoA + NADPH + dioxygen + H+→2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + NADP+ + H2O (EC 1.14.13.149) |
| No genes |
| 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA→2-oxepin-2(3H)-ylideneacetyl-CoA (EC 5.3.3.18) |
| No genes |
| 2-oxepin-2(3H)-ylideneacetyl-CoA + H2O→3-oxo-5,6-didehydrosuberyl-CoA semialdehyde (EC 3.3.2.12) |
| No genes |
| 3-oxo-5,6-didehydrosuberyl-CoA semialdehyde + NADP+ + H2O→3-oxo-5,6-didehydrosuberyl-CoA + NADPH + 2 H+ (EC 1.2.1.91) |
| No genes |
| 3-oxo-5,6-didehydrosuberyl-CoA + coenzyme A→trans-2,3-dehydroadipyl-coA + acetyl-CoA (EC 2.3.1.223) |
| mRNA_5445 (13813) |
| mRNA_6860 (15228) |
Enoyl-CoA hydratase (in reverse):
trans-2,3-dehydroadipyl-coA + H2O→(3S)-hydroxyadipyl-CoA (EC 4.2.1.17) |
| mRNA_2742 (11110) |
| mRNA_3539 (11907) |
| mRNA_6437 (14805) |
| mRNA_8147 (16515) |
3-hydroxyacyl-CoA dehydrogenase:
(3S)-hydroxyadipyl-CoA + NAD+→3-oxoadipyl-CoA + NADH + H+ (EC 1.1.1.35) |
| mRNA_2835 (11203) |
3-oxoadipyl-CoA thiolase (in reverse):
3-oxoadipyl-CoA + coenzyme A→succinyl-CoA + acetyl-CoA (EC 2.3.1.174) |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information