MetaCyc Pathway: lipoate biosynthesis and incorporation I in Rhodosporidium toruloides IFO0880

Add experiment(s):


Lipoyl(octanoyl) transferase:
an octanoyl-[acp] + a [lipoyl-carrier protein]-L-lysine→a [lipoyl-carrier protein] N6-octanoyl-L-lysine + a soluble [acyl-carrier protein] + H+ (EC 2.3.1.181)
mRNA_6453 (14821)
Lipoyl synthase:
a [lipoyl-carrier protein] N6-octanoyl-L-lysine + an [Fe-S] cluster scaffold protein carrying a [4Fe-4S]+2 cluster + 6 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster + 2 S-adenosyl-L-methionine→a [lipoyl-carrier protein]-N6-[(R)-dihydrolipoyl]-L-lysine + 2 5'-deoxyadenosine + 2 S2- + 4 Fe2+ + an [Fe-S] cluster scaffold protein + 2 L-methionine + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 2.8.1.8)
mRNA_5728 (14096)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information