MetaCyc Pathway: sphingosine and sphingosine-1-phosphate metabolism in Rhodosporidium toruloides IFO0880

Add experiment(s):


Ceramidase:
a sphingosine ceramide + H2O→sphingosine + a fatty acid (EC 3.5.1.23)
No genes
Sphinganine kinase:
sphingosine + ATP→sphingosine 1-phosphate + ADP + H+ (EC 2.7.1.91)
No genes
sphingosine 1-phosphate→(2E)-hexadecenal + O-phosphoethanolamine
No genes
sphingosine 1-phosphate + H2O→sphingosine + phosphate
No genes
2-hexadecenal reductase (in reverse):
(2E)-hexadecenal + NADPH + H+→palmitaldehyde + NADP+ (EC 1.3.1.27)
No genes
Aldehyde dehydrogenase (NAD(+)):
(2E)-hexadecenal + NAD+ + H2O→(2E)-hexadecenoate + NADH + 2 H+ (EC 1.2.1.3)
mRNA_2053 (10421)
mRNA_2289 (10657)
mRNA_2380 (10748)
mRNA_2756 (11124)
mRNA_3674 (12042)
mRNA_3891 (12259)
mRNA_4582 (12950)
mRNA_5058 (13426)
mRNA_7446 (15814)
mRNA_7955 (16323)
mRNA_8468 (16836)
mRNA_324 (8692)
Aldehyde dehydrogenase (NAD(+)):
palmitaldehyde + NAD+ + H2O→palmitate + NADH + 2 H+ (EC 1.2.1.3)
mRNA_2053 (10421)
mRNA_2289 (10657)
mRNA_2380 (10748)
mRNA_2756 (11124)
mRNA_3674 (12042)
mRNA_3891 (12259)
mRNA_4582 (12950)
mRNA_5058 (13426)
mRNA_7446 (15814)
mRNA_7955 (16323)
mRNA_8468 (16836)
mRNA_324 (8692)
Long-chain-fatty-acid--CoA ligase:
(2E)-hexadecenoate + ATP + coenzyme A→(2E)-hexadecenoyl-CoA + AMP + diphosphate (EC 6.2.1.3)
mRNA_4187 (12555)
mRNA_7380 (15748)
Acyl-CoA dehydrogenase (NADP(+)) (in reverse):
(2E)-hexadecenoyl-CoA + NADPH + H+→palmitoyl-CoA + NADP+ (EC 1.3.1.8)
No genes
Long-chain-fatty-acid--CoA ligase:
palmitate + ATP + coenzyme A→palmitoyl-CoA + AMP + diphosphate (EC 6.2.1.3)
mRNA_4187 (12555)
mRNA_7380 (15748)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information