MetaCyc Pathway: dTMP de novo biosynthesis (mitochondrial) in Rhodosporidium toruloides IFO0880

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Dihydrofolate reductase (in reverse):
a 7,8-dihydrofolate + NADPH + H+→a tetrahydrofolate + NADP+ (EC 1.5.1.3)
No genes
Glycine hydroxymethyltransferase:
a tetrahydrofolate + L-serine→a 5,10-methylenetetrahydrofolate + glycine + H2O (EC 2.1.2.1)
mRNA_3893 (12261)
mRNA_4293 (12661)
mRNA_4944 (13312)
mRNA_1299 (9667)
Thymidylate synthase:
a 5,10-methylenetetrahydrofolate + dUMP→a 7,8-dihydrofolate + dTMP (EC 2.1.1.45)
mRNA_2476 (10844)
mRNA_2477 (10845)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information