MetaCyc Pathway: superpathway of purine nucleotide salvage in Rhodosporidium toruloides IFO0880

Add experiment(s):


Adenosine kinase:
adenosine + ATP→AMP + ADP + H+ (EC 2.7.1.20)
mRNA_17 (8385)
Purine-nucleoside phosphorylase:
adenosine + phosphate→adenine + α-D-ribose-1-phosphate (EC 2.4.2.1)
mRNA_7908 (16276)
Adenylosuccinate synthase:
IMP + L-aspartate + GTP→adenylo-succinate + GDP + 2 H+ + phosphate (EC 6.3.4.4)
mRNA_3802 (12170)
IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
mRNA_27 (8395)
Purine-nucleoside phosphorylase:
guanosine + phosphate→guanine + α-D-ribose-1-phosphate (EC 2.4.2.1; 2.4.2.15)
mRNA_7908 (16276)
Adenine phosphoribosyltransferase (in reverse):
adenine + 5-phospho-α-D-ribose 1-diphosphate→AMP + diphosphate (EC 2.4.2.7)
mRNA_7825 (16193)
Adenylosuccinate lyase:
adenylo-succinate→AMP + fumarate (EC 4.3.2.2)
mRNA_7437 (15805)
GMP synthase (glutamine-hydrolyzing):
XMP + ATP + L-glutamine + H2O→GMP + AMP + L-glutamate + diphosphate + 2 H+ (EC 6.3.5.2)
mRNA_7388 (15756)
Hypoxanthine phosphoribosyltransferase (in reverse):
guanine + 5-phospho-α-D-ribose 1-diphosphate→GMP + diphosphate (EC 2.4.2.8)
mRNA_7825 (16193)
Adenylate kinase:
AMP + ATP→2 ADP (EC 2.7.4.3)
mRNA_3932 (12300)
mRNA_4072 (12440)
mRNA_4822 (13190)
mRNA_5739 (14107)
mRNA_6761 (15129)
mRNA_7128 (15496)
mRNA_7396 (15764)
mRNA_1365 (9733)
Guanylate kinase:
GMP + ATP→GDP + ADP (EC 2.7.4.8)
mRNA_3157 (11525)
Ribonucleoside-diphosphate reductase (in reverse):
ADP + a reduced thioredoxin→dADP + an oxidized thioredoxin + H2O (EC 1.17.4.1)
mRNA_2804 (11172)
mRNA_2922 (11290)
mRNA_5869 (14237)
Nucleoside-diphosphate kinase:
GDP + ATP→GTP + ADP (EC 2.7.4.6)
mRNA_7311 (15679)
mRNA_575 (8943)
Nucleoside-diphosphate kinase:
dADP + ATP→ADP + dATP (EC 2.7.4.6)
mRNA_7311 (15679)
mRNA_575 (8943)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information