MetaCyc Pathway: L-lysine degradation II (L-pipecolate pathway) in Rhodosporidium toruloides IFO0880

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L-lysine oxidase:
L-lysine + dioxygen + H2O→6-amino-2-oxohexanoate + ammonium + hydrogen peroxide (EC 1.4.3.14)
No genes
L-lysine + 2-oxoglutarate→6-amino-2-oxohexanoate + L-glutamate
No genes
6-amino-2-oxohexanoate→1-piperideine-2-carboxylate + H+ + H2O (spontaneous)
No genes
Pyrroline-2-carboxylate reductase (in reverse):
1-piperideine-2-carboxylate + NAD(P)H + 2 H+→L-pipecolate + NAD(P)+ (EC 1.5.1.1)
No genes
L-pipecolate oxidase:
L-pipecolate + dioxygen→1-piperideine 6-carboxylate + hydrogen peroxide + H+ (EC 1.5.3.7)
No genes
L-aminoadipate-semialdehyde dehydrogenase:
1-piperideine 6-carboxylate + NAD(P)+ + 2 H2O→L-2-aminoadipate + NAD(P)H + H+ (EC 1.2.1.31)
mRNA_7446 (15814)
mRNA_1127 (9495)
1-piperideine 6-carboxylate + NADPH + 2 H+→L-pipecolate + NADP+
No genes
2-aminoadipate transaminase:
L-2-aminoadipate + 2-oxoglutarate→2-oxoadipate + L-glutamate (EC 2.6.1.39)
No genes
2-oxoadipate + coenzyme A + NAD+→glutaryl-CoA + CO2 + NADH (EC 1.2.1.105)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information