MetaCyc Pathway: superpathway of L-threonine biosynthesis in Rhodosporidium toruloides IFO0880

Add experiment(s):


Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1)
mRNA_5562 (13930)
mRNA_5913 (14281)
mRNA_7697 (16065)
mRNA_172 (8540)
mRNA_568 (8936)
mRNA_1267 (9635)
Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP (EC 2.7.2.4)
mRNA_6294 (14662)
mRNA_8370 (16738)
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate (EC 1.2.1.11)
mRNA_1962 (10330)
Homoserine dehydrogenase (in reverse):
L-aspartate 4-semialdehyde + NAD(P)H + H+→L-homoserine + NAD(P)+ (EC 1.1.1.3)
mRNA_3712 (12080)
mRNA_6294 (14662)
mRNA_8370 (16738)
Homoserine kinase:
L-homoserine + ATP→O-phospho-L-homoserine + ADP + H+ (EC 2.7.1.39)
mRNA_283 (8651)
Threonine synthase:
O-phospho-L-homoserine + H2O→L-threonine + phosphate (EC 4.2.3.1)
mRNA_1374 (9742)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information