MetaCyc Pathway: L-tyrosine degradation I in Rhodosporidium toruloides IFO0880

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
mRNA_4039 (12407)
mRNA_4862 (13230)
mRNA_5562 (13930)
mRNA_5913 (14281)
mRNA_7697 (16065)
mRNA_172 (8540)
mRNA_568 (8936)
mRNA_1267 (9635)
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2
(EC 1.13.11.27)
No genes
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+
(EC 1.13.11.5)
mRNA_7338 (15706)
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate
(EC 5.2.1.2)
No genes
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+
(EC 3.7.1.2)
mRNA_3594 (11962)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information