| Role | Gene | Name | |
|---|
| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) | No genes | | |
| 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | mRNA_4194 | 12562 | |
| 5-nucleotidase SurE (EC 3.1.3.5) | No genes | | |
| 6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) | No genes | | |
| ATPase component of general energizing module of ECF transporters | No genes | | |
| Alternative Folylglutamate Synthase | No genes | | |
| Alternative dihydrofolate reductase 2 | No genes | | |
| Alternative dihydrofolate reductase 3 | No genes | | |
| Aminodeoxychorismate lyase (EC 4.1.3.38) | No genes | | |
| COG0488: ATPase components of ABC transporters with duplicated ATPase domains | No genes | | |
| Dihydrofolate reductase (EC 1.5.1.3) | No genes | | |
| Dihydrofolate synthase (EC 6.3.2.12) | No genes | | |
| Dihydroneopterin aldolase (EC 4.1.2.25) | No genes | | |
| Dihydroneopterin triphosphate epimerase | No genes | | |
| Dihydroneopterin triphosphate pyrophosphohydolase | No genes | | |
| Dihydroneopterin triphosphate pyrophosphohydolase type 2 | No genes | | |
| Dihydropteroate synthase (EC 2.5.1.15) | No genes | | |
| FolM Alternative dihydrofolate reductase 1 | No genes | | |
| Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) | No genes | | |
| Folate transporter 3 | No genes | | |
| Folylpolyglutamate synthase (EC 6.3.2.17) | No genes | | |
| Formate--tetrahydrofolate ligase (EC 6.3.4.3) | mRNA_6998 | 15366 | |
| GTP cyclohydrolase I (EC 3.5.4.16) type 1 | mRNA_1964 | 10332 | |
| GTP cyclohydrolase I (EC 3.5.4.16) type 2 | No genes | | |
| Methionyl-tRNA formyltransferase (EC 2.1.2.9) | mRNA_3531 | 11899 | |
| | mRNA_1475 | 9843 | |
| Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) | mRNA_4257 | 12625 | |
| | mRNA_6998 | 15366 | |
| Non functional Dihydropteroate synthase 2 | No genes | | |
| Nucleoside triphosphate pyrophosphohydrolase MazG | No genes | | |
| Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) | mRNA_5301 | 13669 | |
| Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) | mRNA_5301 | 13669 | |
| PqqC-like protein | No genes | | |
| Putative DHNTP pyrophosphatase | No genes | | |
| Related to Dihydropteroate synthase | No genes | | |
| Serine hydroxymethyltransferase (EC 2.1.2.1) | mRNA_3893 | 12261 | |
| | mRNA_4293 | 12661 | |
| | mRNA_4944 | 13312 | |
| | mRNA_1299 | 9667 | |
| Substrate-specific component FolT of folate ECF transporter | No genes | | |
| Thymidine kinase (EC 2.7.1.21) | No genes | | |
| Thymidylate synthase (EC 2.1.1.45) | mRNA_2477 | 10845 | |
| Thymidylate synthase thyX (EC 2.1.1.-) | No genes | | |
| Transaldolase (EC 2.2.1.2) | mRNA_1805 | 10173 | |
| Transmembrane component of general energizing module of ECF transporters | No genes | | |
| Xanthosine/inosine triphosphate pyrophosphatase | No genes | | |
| alternate gene name: yzbB | No genes | | |